"The past few months have been a difficult time for me personally and it has taken a toll," the Brazilian star wrote on Instagram.
"As such, I've decided to withdraw from the start of the 2022 WSL Championship Tour.
"I had every intention of competing for the full season, had made all the preparations medically (I took my COVID vaccination during my holidays) and mentally and physically, but I'm not in a place where I believe I can perform against the world's best surfers right now and I need to focus on my well-being.
"I don't know how long it will take, but I aim to return to the Championship Tour as soon as I am ready.
"I very much appreciate everyone's ongoing love and support. I'll be back when I am able."
World Surf League CEO Erik Logan said the organisation supported Medina's decision to take a break.
"The health and safety of our athletes is of the utmost importance, and we fully support Gabriel’s decision to prioritise his well-being,” Logan said.
"We want to put the world’s best surfers in front of our fans to start the season, but we certainly respect his decision."